Purpose

The Investigator seeks to evaluate the long term neurological and pulmonary sequelae of COVID-19.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Clinically suspected or laboratory confirmed COVID-19 infection by real-time PCR - Admission to an intensive care unit for COVID-19 and discharge

Exclusion Criteria

  • Pregnancy - Participants unable to complete long-term follow-up due to logistical problems - Participant paralyzed before being admitted to hospital for COVID-19 - History of pulmonary resection - Previous pulmonary transplant - Documented advanced neurologic order for which the patient is unable to carry out 6 minute walk test - Documented psychiatric disease for which the patient is unable to carry out interview

Study Design

Phase
Study Type
Observational
Observational Model
Case-Only
Time Perspective
Prospective

Recruiting Locations

Johns Hopkins Hospital
Baltimore, Maryland 21287
Contact:
Sung-Min Cho, DO, MHS
410-955-2611
csungmi1@jhmi.edu

More Details

NCT ID
NCT05175339
Status
Recruiting
Sponsor
Johns Hopkins University

Study Contact

Sung-Min Cho, DO, MHS
410-955-2611
csungmi1@jhmi.edu

Detailed Description

Recent data suggests that survivors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or (COVID-19) report adverse health status, including neurological and cognitive deficits and impaired pulmonary function, even months after discharge. Adult COVID-19 survivors after ICU stay, who are noted to have increased mortality and organ failure, are at higher risk of long-term disabilities and impaired quality of life. This study is one branch of a multi-site study coordinated by Gilead Sciences, in which participants who were critically ill with COVID-19 will be followed at three and nine months after discharge to test pulmonary function, cognitive function, and quality of life.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.