Long-term Impact in Intensive Care Survivors of Coronavirus Disease (COVID-19)
Purpose
The Investigator seeks to evaluate the long term neurological and pulmonary sequelae of COVID-19.
Condition
- COVID-19
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Clinically suspected or laboratory confirmed COVID-19 infection by real-time PCR - Admission to an intensive care unit for COVID-19 and discharge
Exclusion Criteria
- Pregnancy - Participants unable to complete long-term follow-up due to logistical problems - Participant paralyzed before being admitted to hospital for COVID-19 - History of pulmonary resection - Previous pulmonary transplant - Documented advanced neurologic order for which the patient is unable to carry out 6 minute walk test - Documented psychiatric disease for which the patient is unable to carry out interview
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Case-Only
- Time Perspective
- Prospective
Recruiting Locations
More Details
- NCT ID
- NCT05175339
- Status
- Completed
- Sponsor
- Johns Hopkins University
Detailed Description
Recent data suggests that survivors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or (COVID-19) report adverse health status, including neurological and cognitive deficits and impaired pulmonary function, even months after discharge. Adult COVID-19 survivors after ICU stay, who are noted to have increased mortality and organ failure, are at higher risk of long-term disabilities and impaired quality of life. This study is one branch of a multi-site study coordinated by Gilead Sciences, in which participants who were critically ill with COVID-19 will be followed at three and nine months after discharge to test pulmonary function, cognitive function, and quality of life.