CD2H COVID-19

Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure

Purpose

The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.

Condition

COVID 19

Eligibility

Eligible Ages: Under 17 Years
Eligible Genders: All
Accepts Healthy Volunteers: No

Inclusion Criteria

Patients 0-17 years of age, 10 kg or greater, with suspected or confirmed Covid-19 respiratory failure requiring endotracheal intubation and mechanical ventilation admitted to Mayo Clinic Hospital, St. Mary's Campus Pediatric Intensive Care Unit.

Exclusion Criteria

Patients <10 kg - Patients with pre-existing chronic mechanical ventilation (chronic respiratory failure) - Patients with known esophageal disease (strictures, known esophageal anatomic abnormalities) - Patients with severe coagulopathy (for which placement of esophageal balloon or other gastric tube via nose or mouth is contraindicated) - Patients who are pregnant (as determined by standard pregnancy testing criteria for Pediatric ICU admission).

Study Design

Phase: N/A
Study Type: Interventional
Allocation: N/A
Intervention Model: Single Group Assignment
Primary Purpose: Other
Masking: None (Open Label)

Arm Groups

Arm	Description	Assigned Intervention
Experimental Intubated pediatric patients with COVID-19 respiratory failure		Diagnostic Test: Transpulmonary pressure measurements Transpulmonary pressure measurements

More Details

NCT ID: NCT04519411
Status: Withdrawn
Sponsor: Mayo Clinic

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.