Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure

Purpose

The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.

Condition

  • COVID 19

Eligibility

Eligible Ages
Under 17 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients 0-17 years of age, 10 kg or greater, with suspected or confirmed Covid-19 respiratory failure requiring endotracheal intubation and mechanical ventilation admitted to Mayo Clinic Hospital, St. Mary's Campus Pediatric Intensive Care Unit.

Exclusion Criteria

  • Patients <10 kg - Patients with pre-existing chronic mechanical ventilation (chronic respiratory failure) - Patients with known esophageal disease (strictures, known esophageal anatomic abnormalities) - Patients with severe coagulopathy (for which placement of esophageal balloon or other gastric tube via nose or mouth is contraindicated) - Patients who are pregnant (as determined by standard pregnancy testing criteria for Pediatric ICU admission).

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Other
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Intubated pediatric patients with COVID-19 respiratory failure
  • Diagnostic Test: Transpulmonary pressure measurements
    Transpulmonary pressure measurements

More Details

NCT ID
NCT04519411
Status
Withdrawn
Sponsor
Mayo Clinic