Eligibility

Eligible Ages

All ages

Eligible Sex

All

Accepts Healthy Volunteers

Yes

Criteria

Community Testing Component:

Inclusion:

- All community members are able to participate in the community testing component.

Exclusion:

- There is no exclusion criteria and participants will not be excluded based on pregnancy
status or age.

For Component A:

Inclusion:

- All ages

- AND Lives in service area of a recruitment center (i.e., within range of courier
pick up)

- AND Plans to remain living in a recruitment area for the next 2 years.

Exclusion:

- Inability to communicate in a language in which consent forms, materials, etc. are
available

- OR Incarcerated

- OR Living in a congregate setting (e.g., assisted living, nursing home, university
dormitories with shared bathroom and communal eating facilities)

- OR Unable/unwilling to participate in planned data and specimen collections

- OR Unable to comply with study procedures, as determined by study investigators

- OR Participation in clinical trials of investigational agents for respiratory viral
infections during the three months prior to enrollment and for the duration of the
study.

For Component B:

Inclusion:

Index case:

- Detection of priority respiratory pathogen via laboratory or point-of-care test on
the day of eligibility screening or in the previous 5 days, AND

- Lives in service area of a recruitment center (i.e., within range of courier pick
up), AND

- Lives in a household with ≥1 other person and plans to remain in the household for
at least the duration of specimen collection (i.e., 14 days), AND

- Has not been hospitalized since the date of symptom onset.

Household contacts:

- Routinely sleep in the same household as index case and slept in household ≥1 night
in the 7 days before index case symptom onset, AND

- Plan to remain in the household for at least the duration of specimen collection
(i.e., 14 days).

Household:

- There is ≥1 non-ill household member (i.e., asymptomatic and has not tested positive
for the virus of the index case) on the day of eligibility screening or in the
previous 5 days,

- AND all symptomatic persons in the household had a symptom or diagnosis onset date
on the day of eligibility screening or in the previous 5 days.

Exclusion:

Index case:

- Lives in a congregate setting (e.g., assisted living, nursing home, university
dormitories with shared bathroom and communal eating facilities)

- Meet any A1 exclusion criteria

Household contacts:

- Has been hospitalized any time since date of primary case symptom onset

- Meets any A1 exclusion criteria

Household:

- The enrollment visit occurs >6 days after the first symptom onset of primary case

- The primary case in the household is not enrolled

- The primary case has been hospitalized any time after the date of symptom onset