Asymptomatic and Pre-symptomatic Transmission of SARS-CoV-2 in a Community Congregant Setting
Purpose
The overall aim of this study is to measure how transmission of COVID-19 occurs in communities - including the role of super spreaders and/or identifying conditions that may increase transmission risk, with a focus on congregant situations. In order to identify how presence of symptoms and behavior affects the transmissibility of the virus, the investigators will measure SARS-CoV-2 in exhaled breath of asymptomatic and symptomatic persons using polyvinyl alcohol (PVA) test strips embedded in face masks (Face Mask Sampling- "FMS") - an innovative, non-invasive method for detection of SARS-CoV-2 in exhaled air.
Conditions
- COVID-19
- SARS-CoV2 Infection
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Individuals age ≥ 18 years of any gender tested positive for SARS-CoV-2 by a molecular reference test (PCR test or antigen test) [INDEX PATIENTS] - Individuals age ≥ 18 years and known to be contacts of the index patients [CONTACTS]
Exclusion Criteria
- < age 18 years old, unable to wear a face mask due to underlying condition, not able to consent, pregnancy. In addition, signs of severe disease present at time of enrollment (e.g. difficulty breathing, pain when breathing, tightness of chest or developing irregular heart beat).
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
Arm | Description | Assigned Intervention |
---|---|---|
College Students | Collegiate students tested positive for SARS-CoV-2 by a molecular reference test (PCR test or antigen test) (index patients). Collegiate students known to be contacts of the index patients. |
|
Recruiting Locations
Anschutz Medical Campus
Aurora, Colorado 80045
Aurora, Colorado 80045
University of Colorado, Boulder
Boulder, Colorado 80309
Boulder, Colorado 80309
University of Colorado, Colorado Springs
Colorado Springs, Colorado 80918
Colorado Springs, Colorado 80918
Colorado State University
Fort Collins, Colorado 80523
Fort Collins, Colorado 80523
Contact:
Jeannine Riess
970-491-6121
Jeannine Riess
970-491-6121
More Details
- NCT ID
- NCT05145803
- Status
- Unknown status
- Sponsor
- Colorado School of Public Health