Purpose

This disparities-focused study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among African Americans residing in Flint, Michigan. This iteration will consider individuals recruited from the Flint Registry and assess willingness to participate in a drive-up saliva sample collection taking place at a central location in Flint, Michigan.

Condition

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • African American or White, 18 or older, and enrolled in the Flint Registry

Exclusion Criteria

  • All who do not meet inclusion criteria.

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Single Group Assignment
Intervention Model Description
Design is partial factorial. All white participants and half of African American participants will receive general video education/messaging. Half of African American participants will be assigned to an intervention condition that includes culturally-targeted information about SARS-CoV-2 antibody testing.
Primary Purpose
Screening
Masking
Single (Participant)
Masking Description
Participants will be unaware of their assignment to a general versus culturally targeted condition.

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
White Flint Registry: General
White participants receive "general consumption" video information about SARS-CoV-2 antibody testing.
  • Behavioral: General SARS-CoV-2 Communication
    SARS-CoV-2 video tutorial is for general consumption and does not include culturally targeted information
Active Comparator
African American Registry: General
African American participants receive "general consumption" video information about SARS-CoV-2 antibody testing.
  • Behavioral: General SARS-CoV-2 Communication
    SARS-CoV-2 video tutorial is for general consumption and does not include culturally targeted information
Experimental
African American Registry: Culturally Targeted
African American participants receive culturally targeted video information about SARS-CoV-2 antibody testing.
  • Behavioral: Culturally Targeted SARS-CoV-2 Communication
    SARS-CoV-2 video tutorial includes a one minute video based messaging adjunct meant to enact a culturally targeted framing of health information presented to African Americans.

Recruiting Locations

More Details

NCT ID
NCT04957082
Status
Completed
Sponsor
Michigan State University

Detailed Description

African Americans develop and die from SARS-CoV-2 infection more than any other racial group in the United States, including in majority African American cities such as Flint, Michigan. Addressing these disparities may be aided by SARS-CoV-2 antibody testing. However, African Americans may be reluctant to partake in conventional antibody testing programs due to medical mistrust and experiences with racism. This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing. The central hypothesis is that African-Americans will be more receptive to antibody testing when benefits and limitations are communicated in a culturally effective manner. Our clinical trial aims are to 1) develop and compare effects of a general versus culturally-targeted video about antibody testing on African American and White Flint residents' antibody testing attitudes and uptake; 2) identify and compare effects of a general versus culturally-targeted video on activation of medical mistrust and racism-related cognition among African Americans when considering antibody testing. In collaboration with clinical and community partners, we have prepared and will evaluate general and culturally-targeted video tutorials about SARS-CoV-2 antibody testing. These brief videos will be distributed to the Flint community through the Flint Registry - a highly visible local health resource exchange. We will furnish an opportunity to engage salivary antibody screening and measure willingness to participate. In this study iteration, we will consider willingness to participate in a drive-up saliva sample collection that is taking place at a central location in Flint, Michigan.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.