Purpose

The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have suspected COVID symptoms at the time of their test. Participants will complete short online surveys every 3 months for 18 months, share information about their health using a secure web-based platform, and are compensated for their time.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  1. Fluent in English or Spanish; 2. Age 18 and over; 3. Self-reported symptoms suggestive of acute SARSCOV2 infection; 4. Under investigation for SARSCOV2 (defined as a patient who has received any screening or diagnostic test used to detect the presence of COVID19 including any FDA approved or authorized molecular or antigen-based assay) within the last 42 days.

Exclusion Criteria

  1. Unable to provide informed consent; 2. Study team unable to confirm result of diagnostic test for SARSCOV2; 3. Does not have access to a hand-held device or computer that would allow for digital participation in the study; 4. Individuals who are prisoners while participating in the study.

Study Design

Phase
Study Type
Observational [Patient Registry]
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Symptomatic Individuals with infection with SARS-COV2 (ie exposed cohort) Symptomatic Individuals test positive for SARS-COV2. Participants will be enrolled soon after infection and followed to assess for long term outcomes.
Symptomatic Individuals without infection with SARS-COV2 (ie unexposed cohort) Symptomatic Individuals test negative for SARS-COV2. Participants will be enrolled soon after testing and followed to assess for long term outcomes.

Recruiting Locations

UCLA
Los Angeles, California 90024
Contact:
Michelle L'Hommedieu, PhD
310-694-7503
COVIDInspire@mednet.ucla.edu

UCSF
San Francisco, California 94110
Contact:
Robin Kemball
415-508-8354
inspire@ucsf.edu

Yale
New Haven, Connecticut 06510
Contact:
Jeremy Kinsman
475-222-2345
Inspire@yale.edu

Rush University Medical Center
Chicago, Illinois 60612
Contact:
Michelle Santangelo
312-952-6615
Inspire@rush.edu

Thomas Jefferson University
Philadelphia, Pennsylvania 19107
Contact:
Morgan Kelly
215-531-2106
morgan.kelly2@jefferson.edu

University of Texas Southwestern
Dallas, Texas 75390
Contact:
Paula Arellano-Cruz
214-648-2675
INSPIRE_EMRESEARCH@UTSOUTHWESTERN.EDU

University of Texas Health Science Center at Houston
Houston, Texas 77030
Contact:
Leslie Johnson
713-500-7875
UTINSPIRE@uth.tmc.edu

University of Washington
Seattle, Washington 98104
Contact:
Rachel Geyer
206-543-3240
inspireregistry@uw.edu

More Details

NCT ID
NCT04610515
Status
Recruiting
Sponsor
Rush University Medical Center

Study Contact

Katherine Koo
312-952-6615
inspire@rush.edu

Detailed Description

This study will use a digital platform to longitudinally track comprehensive information including patient self-report as well as data that describe the process and outcome of care in the electronic medical record (EMR) of a large representative sample of patients under investigation for SARSCOV2. The objective is to generate knowledge rapidly using digital tools and collaborative sciences to produce real-time data, analysis, and reporting compared to more traditional approaches. An additional goal is to promote an open science approach whereby scientists, with proper approvals and in line with the permissions granted by the participants, have the opportunity to work with data in ways that protect individual privacy but promote rapid dissemination and implementation of knowledge.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.