CD2H COVID-19

Breath Analysis Based Disease Biomarkers of COVID-19 and Other Diseases

Purpose

The purpose of the study is to develop a clinical test based on breath analysis that can be used for disease diagnosis or prognosis.

Conditions

Liver Diseases
Liver Cancer
COVID19

Eligibility

Eligible Ages: Over 18 Years
Eligible Genders: All
Accepts Healthy Volunteers: Yes

Inclusion Criteria

Able to provide informed consent

Exclusion Criteria

None

Study Design

Phase
Study Type: Observational
Observational Model: Cohort
Time Perspective: Prospective

Arm Groups

Arm	Description	Assigned Intervention
Normal	No known medical conditions	Diagnostic Test: Collection of breath sample Analysis of volatile organic compounds in breath
Liver Cirrhosis	Clinically diagnosed with cirrhosis	Diagnostic Test: Collection of breath sample Analysis of volatile organic compounds in breath
COVID-19 tested	Persons with known test results for COVID-19 RNA	Diagnostic Test: Collection of breath sample Analysis of volatile organic compounds in breath
Other	Persons with other medical diagnosis, no known liver disease, negative for COVID-19	Diagnostic Test: Collection of breath sample Analysis of volatile organic compounds in breath

Recruiting Locations

More Details

NCT ID: NCT04341012
Status: Completed
Sponsor: Mayo Clinic

Detailed Description

The study will seek to collect and analyze breath samples from a broad range of patients to develop reference ranges and to refine the testing methods. Protocols for breath sample collection and algorithms for analysis will be developed. Samples will be collected from normal volunteers, persons with documented liver disease, organ transplant or with known COVID-19 test results.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.