Antimicrobial Resistance During the SARS-CoV-2 (COVID-19) Pandemic

Purpose

Assess the incidence and rates of resistant pathogens prior to and during the COVID-19 pandemic.

Condition

  • COVID-19

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • • Patients admitted to Methodist Richardson, Methodist Mansfield, Methodist Charlton, or Methodist Dallas Medical Centers between March 2018 and August 2021. - >18 years old

Exclusion Criteria

  • • Outpatient visit - Not admitted to an inpatient or observation status

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Recruiting Locations

More Details

NCT ID
NCT06334731
Status
Completed
Sponsor
Methodist Health System

Detailed Description

The COVID-19 pandemic accelerated/exacerbated resistance rates for key pathogens. Specifically, incidence of extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBLPE), carbapenem-resistant bacteria (CRB), methicillin-resistant Staphyloccoccus aureus (MRSA), vancomycin-resistant Enterococci (VRE), and C. difficile infections (CDI) will be higher in the pandemic time period (Pandemic, March 2020 - February 2025) compared to the pre-pandemic period (Pre-Pandemic, March 2018 - February 2020).