TaiChi-DTx for Treating Long Covid Symptoms

Purpose

The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).

Conditions

  • Fatigue
  • Dyspnea
  • Cognitive Impairment
  • Muscle Pain

Eligibility

Eligible Ages
Between 18 Years and 75 Years
Eligible Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  1. Clinical diagnosis with SARS-CoV2 infection via PCR during the past 3 to 6 months 2. Must be Grade 2 and Grade 3 assessed by the Post-COVID-19 Functional Status (PCFS) Scale

Exclusion Criteria

  1. Admitted in the Intensive Care Unit due to SARS-COV2 infection or any other serve illness 2. Psychiatric diseases and somatic co-morbidities 3. COVID-19 infections or co-morbidities started or exacerbated during the same time

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
To evaluate the effectiveness of Multi-domain Tai Chi Digital Therapy for treating the long term sequalae symptoms among COVID-19 survivors compared with traditional Tai Chi exercise only as control.
Primary Purpose
Supportive Care
Masking
Single (Participant)
Masking Description
The Multi-domain Tai Chi-DTx will be provided via a tablet or smart phone. The traditional Tai Chi exercise with background music and respiratory control exercise with 18 BPM metronome, and 40 Hz sound stimulation will be comprised in a 4-week therapeutic session. A control arm will be designed in this study, which will use the same way to deliver traditional Tai Chi exercise with plain music background only.

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
The Multi-domain Tai Chi Digital Therapy Group 		participants will be provided via a tablet or smart phone the traditional Tai Chi exercise with background music and respiratory control exercise with 18 BPM metronome, and 40 Hz sound stimulation for 4-week therapeutic session.
  • Device: the multi-domain Tai Chi Digital therapy Software Application
    regular Tai Chi exercise, 40 Hz gamma sound stimulation and 18 BPM breath control exercise
Placebo Comparator
The regular Tai Chi Exercise Group 		participants will be provided by the same way to deliver traditional Tai Chi exercise with plain music background, but without respiratory control exercise or 40 Hz sound stimulation. All participants will receive any other routine care or treatment as usual (TAU).
  • Device: the multi-domain Tai Chi Digital therapy Software Application
    regular Tai Chi exercise, 40 Hz gamma sound stimulation and 18 BPM breath control exercise

Recruiting Locations

More Details

NCT ID
NCT05419219
Status
Unknown status
Sponsor
Tim Shi

Detailed Description

The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID). This intervention will comprise of traditional Tai Chi physical therapy with background music entraining 40 Hz sound wave and respiratory control training. The Multi-domain Tai Chi Digital Therapy will be delivered via a tablet or smart phone to participants for a 4-week therapeutic cycle. Clinical standardized physical tests and self-scored questionnaires will be collected to understand the change in symptoms, including fatigue, dyspnea, and brain fog, as well as absenteeism.