Total-Body Parametric 18F-FDG PET of COVID-19

Purpose

The primary objective is to measure the change between COVID-19 patients and normal subjects; the secondary objective is to measure the change in COVID-19 patients between baseline and 4-month follow up.

Condition

  • Covid19

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • COVID-19 positive patients will have a previous positive COVID-19 test and radiographic findings, and/or a positive SARS-CoV-2 antibody test and be in early recovery. - First PET/CT visit needs to be within 8 weeks of COVID-19 diagnosis. - Ability to understand and willingness to sign an informed consent form. - Ability to adhere to the study visit schedule and other protocol requirements. - All persons ≥18 years of age.

Exclusion Criteria

  • Pregnant or lactating women. - Any condition that would prohibit the understanding or rendering of informed consent. - Unable to lie supine for 1-hour imaging with PET. - Prisoners. - Any comorbidity that, in the opinion of the investigator, could compromise protocol objectives.

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Basic Science
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
COVID-19 patients
  • Device: uEXPLORER/mCT
    Each participant will undergo two 18F-FDG PET/CT scans, one at baseline and one at 4- month (+/- 2 weeks) follow-up.

Recruiting Locations

More Details

NCT ID
NCT04841707
Status
Completed
Sponsor
University of California, Davis