Long Term Outcomes of Patients With COVID-19

Purpose

The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.

Conditions

  • Critical Illness
  • Corona Virus Infection
  • Respiratory Failure
  • Covid-19

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • adult patients admitted to the ICU

Exclusion Criteria

  • none

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
COVID19 positive ICU patients coronavirus positive
  • Other: Quality of Life
    Physical disability assessment tool
    Other names:
    • SF-36
  • Other: Impact Event Score
    Psychological Sequelae assessment tool
    Other names:
    • IES-R
  • Other: Hospital anxiety and depression scale
    Psychological Sequelae assessment tool
non-COVID19 ICU patients without coronavirus
  • Other: Quality of Life
    Physical disability assessment tool
    Other names:
    • SF-36

Recruiting Locations

More Details

NCT ID
NCT04360538
Status
Active, not recruiting
Sponsor
University of Chicago

Detailed Description

The aim of this proposal to is to understand the extent and degree of physical disability, psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical illness will have upon hospital discharge, 6 months, and up to one year post discharge. These outcomes of interest will be evaluated prospectively. The investigators will perform these measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19 patients with respiratory failure. The investigators also seek to determine the risk factors of these long-term complications in order to guide providers as to which patients should be screened for these deficits. Finally, the investigators will examine the association of various critical care interventions such as invasive versus noninvasive mechanical ventilation or use of sedatives and their effects on disability and cognitive dysfunction.