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A Study to Evaluate the Safety and Immunogenicity of the mRNA COVID-19 Vaccines in Healthy Children Between...
ModernaTX, Inc.
SARS-CoV-2
This study will evaluate the safety and immunogenicity of the mRNA-1273.214 vaccine for
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concerns (VOCs)
in participants aged 6 months to <6 years, when administered as a primary series in
SARS-CoV-2 vaccine-naïve participants... expand
This study will evaluate the safety and immunogenicity of the mRNA-1273.214 vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concerns (VOCs) in participants aged 6 months to <6 years, when administered as a primary series in SARS-CoV-2 vaccine-naïve participants (Part 1) and a single booster dose (BD) given to participants who previously received 2 doses of the mRNA-1273 vaccine as a primary series (Part 2); and will evaluate the safety and immunogenicity of the mRNA-1273.815 vaccine, when administered as a BD in participants aged 6 months to <6 years (Part 3) and when administered to SARS-CoV-2 vaccine-naïve participants aged 2 years to <5 years of age (Part 4). Type: Interventional Start Date: Jun 2022 |
Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome
Vanderbilt University Medical Center
Post-acute COVID-19 Syndrome
Postural Tachycardia Syndrome (POTS)
Long COVID
SARS CoV 2 Infection
The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists
beyond the 3-month convalescence period after COVID-19 infections.
This syndrome affects mostly women (~80%), present with chronic tachycardia and
Orthostatic intolerance symptoms without any identifiable cause.... expand
The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the 3-month convalescence period after COVID-19 infections. This syndrome affects mostly women (~80%), present with chronic tachycardia and Orthostatic intolerance symptoms without any identifiable cause. In addition, non-specific symptoms such as fatigue, headache, and "brain fog", commonly described in POTS patients are also present in this novel condition, recently named post-COVID-19 tachycardia syndrome, POTS variant. Reduced Vagal activity and unresolved inflammation is post-COVID-19 POTS is hypothesized as the cause of Long COVID Type: Interventional Start Date: Jun 2022 |
The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic...
Icahn School of Medicine at Mount Sinai
Pulmonary Fibrosis
Interstitial Lung Disease
Respiratory Disease
This is a collaborative study between Icahn School of Medicine at Mount Sinai, Boehringer
Ingelheim Pharmaceuticals and up to 9 other clinical centers across the US to determine
the effect of nintedanib on slowing the rate of lung disease in patients who have been
diagnosed with COVID-19, and have... expand
This is a collaborative study between Icahn School of Medicine at Mount Sinai, Boehringer Ingelheim Pharmaceuticals and up to 9 other clinical centers across the US to determine the effect of nintedanib on slowing the rate of lung disease in patients who have been diagnosed with COVID-19, and have ongoing lung injury more than 30 days out from their diagnosis. Required one of the following after diagnosis with SARS-CoV-2: supplemental oxygen by nasal cannula, high flow oxygen, non invasive ventilation such as CPAP or BIPAP, or mechanical ventilation or a history of desaturation below 90%. Type: Interventional Start Date: Nov 2020 |
Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
National Institute of Allergy and Infectious Diseases (NIAID)
Influenza
Respiratory Virus
Coronavirus
Background:
Respiratory viruses circulate throughout the year and around the globe. Wearable and
sensor devices, like smartwatches, may be able to help monitor infectious diseases.
Researchers want to use them to learn how respiratory viruses affect people in different
ways.
Objective:
To... expand
Background: Respiratory viruses circulate throughout the year and around the globe. Wearable and sensor devices, like smartwatches, may be able to help monitor infectious diseases. Researchers want to use them to learn how respiratory viruses affect people in different ways. Objective: To use digital devices to collect data from participants in challenge studies that could indicate subtle changes in health during an infection that might otherwise go unnoticed. Eligibility: Healthy adults who have enrolled in a challenge study. Design: Participants will stay at NIH for at least 9 days and then they will have outpatient visits. While at NIH, participants will wear a smartwatch at all times. It will record data like temperature, heart rate, breathing rate, and movements. Participants will have 2 smartphones. One will be recording at all times to listen for coughing. Participants will use the other smartphone to check their vital signs. They will collect data like heart rate, temperature, and the level of oxygen in the blood every 4 hours during the daytime. Participants will perform tasks every 4 hours during the daytime. They will record themselves coughing, breathing in deeply, and reading aloud. They will take pictures and videos of their face. A bedside sensor will record participants while they sleep. It will record heart rate and breathing rate. It will also look at sleep activity, such as movements participants make during sleep and how deeply they sleep. Participants sharing the same room will be exposed to the same challenge virus. For outpatient visits, participants will use one smartphone and the smartwatch to complete the above tasks. Participation will last from 10 weeks to 1 year. Type: Observational Start Date: Oct 2023 |
Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)
Rush University Medical Center
Covid19
ME/CFS
SARS COV2
Novel Coronavirus Infection
Neurocognitive Disorders
The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study
is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently
tested adults, both negative and positive, who have suspected COVID symptoms at the time
of their test. Participants will... expand
The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have suspected COVID symptoms at the time of their test. Participants will complete short online surveys every 3 months for 18 months, share information about their health using a secure web-based platform, and are compensated for their time. Type: Observational [Patient Registry] Start Date: Dec 2020 |
Serological Surveillance for COVID-19 in Central North Carolina
National Institute of Environmental Health Sciences (NIEHS)
COVID-19
Background:
The SARS-CoV-2 virus has caused a pandemic. Little is known about the virus, so data is
needed to form an effective public health response. Researchers want to count how many
people have been exposed to COVID-19, learn about symptoms, and find out how many
antibodies to the SARS-CoV-2... expand
Background: The SARS-CoV-2 virus has caused a pandemic. Little is known about the virus, so data is needed to form an effective public health response. Researchers want to count how many people have been exposed to COVID-19, learn about symptoms, and find out how many antibodies to the SARS-CoV-2 virus a person may have in their blood over 1 year. This data could affect the response to current and future pandemics. Objective: To learn how many people from a sampling of adults in North Carolina develop antibodies to the SARS-CoV-2 virus over 1 year. Eligibility: Healthy people age 18 and older who do not currently have COVID-19 Design: Participants will be screened with questions about their health. Participants will have five 30-minute visits at the Clinical Research Unit. At each visit, they will have blood drawn to see if they have SARS-CoV-2 antibodies. If the test result is positive for antibodies, the participant will be tested to see if they currently have COVID-19. For this, a nasal or throat swab will be done, or saliva will be collected. They may do this test at the same visit as the blood draw, or they may schedule an extra visit. Around the time of their study visits, participants will take an online survey about themselves, their health, and COVID-19. It takes 10 minutes to complete. Every week for 52 weeks, they will also take a brief online survey about their symptoms. It takes 2 minutes to complete. They will be emailed a link to log in and fill out the surveys on a secure website. Participation will last for 1 year. ... Type: Observational Start Date: Aug 2020 |
A Longitudinal Study of COVID-19 Sequelae and Immunity
National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19
Background:
COVID-19 is a disease caused by the SARS-CoV-2 virus. It infects the respiratory tract.
Some people who get COVID-19 have only mild symptoms. But for others, infection leads to
pneumonia, respiratory failure, and, in some cases, death. Researchers want to learn more
about any effects... expand
Background: COVID-19 is a disease caused by the SARS-CoV-2 virus. It infects the respiratory tract. Some people who get COVID-19 have only mild symptoms. But for others, infection leads to pneumonia, respiratory failure, and, in some cases, death. Researchers want to learn more about any effects that may persist after people recover from COVID-19. Objective: To learn about any long-term medical problems that people who have recovered from COVID-19 might have, and whether they develop an immune response to SARS-CoV-2 that provides protection against reinfection. Eligibility: People age 18 and older who have recovered from documented COVID-19 or were in close contact with someone who had COVID-19 but did not get the infection Design: Participants will be screened over 2 visits. During visit 1, they will answer questions about any symptoms they are having and will be tested for SARS-CoV-2 infection which will involve a nasal swab sample or other FDA approved test. If the test is negative, they will proceed to the second visit, which will include: Physical examination Medical history Mental health interview (which may be recorded if the participant agrees) Chest x-ray (for recovered COVID-19 participants only) Blood and urine tests Pregnancy test (if needed) Lung function test (for recovered COVID-19 participants only) 6-minute walk test (for recovered COVID-19 participants only) Questionnaires about their general and mental health Leukapheresis to collect white blood cells (optional). Participants will be put into 1 of 2 groups: the COVID-19 group or the close contact group. Participants will have study visits every 6 months for 3 years. They will repeat some of the screening tests. Participants in the COVID-19 group may have visits more often if they develop symptoms that suggest re-infection with SARS-CoV-2. Type: Observational Start Date: Jun 2020 |
Mobile Health and COVID-19
University of Houston
Anxiety Depression
The proposed research focuses on evaluating the mobile application, Easing Anxiety
Sensitivity for Everyone (EASE), to improve overall public health that concerns risks and
mental health status during the COVID-19 pandemic and to minimize the existing health
disparities among Black, Latinx, and American... expand
The proposed research focuses on evaluating the mobile application, Easing Anxiety Sensitivity for Everyone (EASE), to improve overall public health that concerns risks and mental health status during the COVID-19 pandemic and to minimize the existing health disparities among Black, Latinx, and American Indian (BLAI) individuals during this time. EASE provides COVID-19 symptom monitoring, exposure management skills, and psychoeducation on stress and it's impact on infection and disease susceptibility. This study aims to compare the effect of EASE to an empirical measurement of standard-of-care digital intervention and to identify the effective mechanisms in EASE. Type: Interventional Start Date: Dec 2021 |
A Trial of NT-I7 in COVID-19 (SPESELPIS)
NeoImmuneTech
COVID-19
The main purposes of this study is to determine the following in participants with mild
coronavirus disease 2019 (COVID-19):
- Safety of a single dose of NT-I7
- The immunological effects of NT-I7 on peripheral lymphocyte counts in COVID-19
patients. expand
The main purposes of this study is to determine the following in participants with mild coronavirus disease 2019 (COVID-19): - Safety of a single dose of NT-I7 - The immunological effects of NT-I7 on peripheral lymphocyte counts in COVID-19 patients. Type: Interventional Start Date: Nov 2020 |
Endocrine, Metabolic and Microbiome Influence on the Post COVID-19 Syndrome
The University of Texas Medical Branch, Galveston
Covid19
The aim of this study is characterize the endocrine, metabolic and microbiomes of
patients with post-COVID syndrome and patients that have recovered from COVID without
lingering symptoms. expand
The aim of this study is characterize the endocrine, metabolic and microbiomes of patients with post-COVID syndrome and patients that have recovered from COVID without lingering symptoms. Type: Observational Start Date: May 2021 |
Convalescent Plasma to Stem Coronavirus (CSSC-001)
Johns Hopkins University
Coronavirus
Convalescence
Evaluate the efficacy of treatment with high-titer Anti- SARS-CoV-2 plasma versus control
(SARS-CoV-2 non-immune plasma) in subjects exposed to Coronavirus disease (COVID-19) at
day 28. expand
Evaluate the efficacy of treatment with high-titer Anti- SARS-CoV-2 plasma versus control (SARS-CoV-2 non-immune plasma) in subjects exposed to Coronavirus disease (COVID-19) at day 28. Type: Interventional Start Date: Jun 2020 |
Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA)
Montreal Heart Institute
Corona Virus Infection
This is a phase 3, randomized, double-blind, placebo-controlled multicenter study to
evaluate the efficacy and safety of colchicine in adult patients diagnosed with COVID-19
infection and have at least one high-risk criterion. Approximately 6000 subjects meeting
all inclusion and no exclusion criteria... expand
This is a phase 3, randomized, double-blind, placebo-controlled multicenter study to evaluate the efficacy and safety of colchicine in adult patients diagnosed with COVID-19 infection and have at least one high-risk criterion. Approximately 6000 subjects meeting all inclusion and no exclusion criteria will be randomized to receive either colchicine or placebo tablets for 30 days. Type: Interventional Start Date: Mar 2020 |
Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
University of Massachusetts, Amherst
Covid19
Physical Disability
Older adults and people with underlying medical conditions are at higher risk for
developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae.
The goal of this proposal is to compare the benefits of home-based lower limb heat
therapy to exercise training on cardio-metabolic... expand
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae. The goal of this proposal is to compare the benefits of home-based lower limb heat therapy to exercise training on cardio-metabolic function and mobility in older adults during their convalescence from hospitalization due to SARS-CoV-2. Type: Interventional Start Date: Feb 2021 |
Wearable Assisted Viral Evidence (WAVE) Study A Decentralized, Prospective Study Exploring the Relationship...
Evidation Health
Influenza, Human
COVID-19
Influenza A
Influenza B
Respiratory Syncytial Virus (RSV)
The goal of this decentralized, observational study is to enroll and observe adults in
the contingent United States during the 2023-2024 flu season. The main study objectives
are to create a dataset of paired wearable data, self-reported symptoms, and respiratory
viral infection (RVI) from PCR testing... expand
The goal of this decentralized, observational study is to enroll and observe adults in the contingent United States during the 2023-2024 flu season. The main study objectives are to create a dataset of paired wearable data, self-reported symptoms, and respiratory viral infection (RVI) from PCR testing during the 2023-2024 flu season and to develop algorithm that is able to accurately classify asymptomatic and symptomatic RVI and understand the algorithm's performance metrics. Type: Observational Start Date: Jan 2024 |
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans...
National Human Genome Research Institute (NHGRI)
Heart Disease
Background:
The COVID-19 pandemic infected and killed African Americans at higher rates than other
Americans. Researchers want to understand why.
Objective:
This natural history study will look at how genetic, environmental, and social factors
may predict or affect COVID-19 in African Americans.... expand
Background: The COVID-19 pandemic infected and killed African Americans at higher rates than other Americans. Researchers want to understand why. Objective: This natural history study will look at how genetic, environmental, and social factors may predict or affect COVID-19 in African Americans. Information from this study will be combined with data from the GENE-FORECAST study. Eligibility: African Americans who were previously enrolled in GENE-FORECAST. Design: The study includes a telephone interview and 1 visit to the NIH clinic. Participants may engage in either one or both of these activities. The telephone interview will last 20 minutes. Participants will talk about their experiences during the COVID-19 pandemic. The clinic visit will last up to 4 hours. Participants will have a physical exam. They will have blood and urine tests. They will be tested for COVID-19. A long swab will be inserted into a nostril to get a fluid sample from the back of the nose. They will have noninvasive tests of their blood vessels. One device used is a pen-like probe placed lightly on the wrist. Another is a rubber sleeve placed around a finger while a blood pressure cuff is used on the arm. Participants will have a test to measure the electrical activity in their heart. Stickers attached to wires will be placed on their chest, arms, and legs. Participants will answer more questions about COVID-19. They will talk about their health behavior. They will talk about their family's health and the neighborhood they live in. Other questions will ask how they feel, live, work, and play.... Type: Observational Start Date: Feb 2023 |
COVID-19 Self-testing IMPROVE
Temple University
COVID-19
The study aims to engage community partners to implement IMPROVE intervention and promote
(COVID-19) rapid testing among vulnerable Asian Americans in the Greater Philadelphia
Area and New York City expand
The study aims to engage community partners to implement IMPROVE intervention and promote (COVID-19) rapid testing among vulnerable Asian Americans in the Greater Philadelphia Area and New York City Type: Interventional Start Date: Jun 2023 |
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
Mayo Clinic
Long COVID
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut
microbiome diversity of long-COVID subjects. expand
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects. Type: Interventional Start Date: Aug 2024 |
Cardiopulmonary Exercise Tests in Patients With Long COVID
Sheffield Hallam University
Long COVID
COVID Long-Haul
The value of clinical cardiopulmonary exercise testing (CPET) within healthcare settings
has been established in the last decade. CPET methods remain highly relevant in the
COVID-19 endemic phase and should be used to assess those recovering from COVID-19
(SARS-CoV-2) infection. This diagnostic tool... expand
The value of clinical cardiopulmonary exercise testing (CPET) within healthcare settings has been established in the last decade. CPET methods remain highly relevant in the COVID-19 endemic phase and should be used to assess those recovering from COVID-19 (SARS-CoV-2) infection. This diagnostic tool could play an integral role in disease prognostication and evaluate the integrative response to incremental exercise. Date from such assessments can enable practitioners to characterise cardio-respiratory fitness and identify reasons for physical impairment or abnormal cardio-respiratory function. More than 50% of patients admitted to hospital will experience cardiorespiratory issues and significant morbidity during their recovery and will require significant rehabilitative support. In this context, measurements obtained from an assessment of cardio-respiratory responses to physiological stress could provide insight regarding the integrity of the pulmonary-vascular interface and characterisation of any impairment or abnormal cardio-respiratory function. Current approaches to rehabilitation are being developed on existing knowledge from Severe Acute Respiratory Syndrome (SARS) and Acute Respiratory Distress Syndrome (ARDS) related illness. These provide important insight but do not provide insight into the novel challenges provided by COVID-19. Type: Observational Start Date: Mar 2023 |
Xofluza-Wearables Feasibility-Study
Children's Hospital of Philadelphia
Infection, Coronavirus
Infections
Influenza
Transplant
Infection Viral
The goal of this prospective, interventional, single-center study is to assess whether
the early detection of Influenza with smartwatch algorithms and alerting, rapid testing,
and subsequent Baloxavir treatment demonstrate better post-infection outcomes versus
publicly available- and Centers for Disease... expand
The goal of this prospective, interventional, single-center study is to assess whether the early detection of Influenza with smartwatch algorithms and alerting, rapid testing, and subsequent Baloxavir treatment demonstrate better post-infection outcomes versus publicly available- and Centers for Disease Control (CDC)-derived national statistics for equivalent household populations as well as pediatric kidney, heart, liver, lung transplant recipients and waitlisted patients. Type: Interventional Start Date: Dec 2023 |
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long...
Duke University
Long COVID
Long Covid19
Long Covid-19
This platform protocol is designed to be flexible so that it is suitable for a wide range
of settings within health care systems, for remote settings, and in community settings
where it can be integrated into COVID-19 programs and subsequent treatment plans.
This protocol is a prospective, multi-center,... expand
This platform protocol is designed to be flexible so that it is suitable for a wide range of settings within health care systems, for remote settings, and in community settings where it can be integrated into COVID-19 programs and subsequent treatment plans. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating potential interventions for PASC-mediated cognitive dysfunction. The hypothesis is that PASC associated dysfunction in cognitive domains, such as executive function and attention, may be improved by interventions that selectively focus on enhancing those domains. Type: Interventional Start Date: Sep 2023 |
RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions...
Duke University
Long COVID
Long Covid19
Long Covid-19
This platform protocol is designed to be flexible so that it is suitable for a wide range
of settings within health care systems, for remote settings, and in community settings
where it can be integrated into COVID-19 programs and subsequent treatment plans.
This protocol is a prospective, multi-center,... expand
This platform protocol is designed to be flexible so that it is suitable for a wide range of settings within health care systems, for remote settings, and in community settings where it can be integrated into COVID-19 programs and subsequent treatment plans. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating potential interventions for PASC-mediated cognitive dysfunction. The hypothesis is that PASC-associated dysfunction in cognitive domains, such as executive function and attention, may be improved by interventions that selectively focus on enhancing those domains. This design seeks to evaluate each intervention relative to the Active Comparator. The BrainHQ (alone) arm is important because the intervention is commercially available, accessible, relatively inexpensive, and does not require trained personnel to administer. BrainHQ has been also been proven effective in other studies of cognitive dysfunction such as studies in aging, mild cognitive impairment, traumatic brain injury, among others. The BrainHQ + PASC CoRE arm and the BrainHQ + tDCS arms are suspected to provide cognitive improvements beyond BrainHQ alone through different mechanisms. Both PASC CoRE and tDCS have extensive prior use and have demonstrated utility in improving aspects of cognitive function in other clinical settings.. Type: Interventional Start Date: Sep 2023 |
Sauna for Long Covid
Massachusetts General Hospital
Long COVID
Research suggests that Whole Body Hyperthermia in a sauna-like environment can reduce
symptoms related to post-acute sequelae of SARS-CoV-2 (PASC), or Long Covid. The
investigators aim to study the feasibility and treatment effect of this procedure for
patients experiencing Long Covid symptoms. expand
Research suggests that Whole Body Hyperthermia in a sauna-like environment can reduce symptoms related to post-acute sequelae of SARS-CoV-2 (PASC), or Long Covid. The investigators aim to study the feasibility and treatment effect of this procedure for patients experiencing Long Covid symptoms. Type: Interventional Start Date: Sep 2024 |
Long-Term Sequelae of SARS-COV-2 Infection: Diabetes Mellitus
The University of Texas Health Science Center at San Antonio
COVID-19
Diabete Mellitus
Hospitalized patients with severe COVID-19 have an increased incidence of insulin
resistance, impaired beta cell function, glucose intolerance (prediabetes), and overt
type 2 diabetes (T2D) compared to non-hospitalized patients with COVID-19 and COVID-19
negative individuals on long-term follow up. expand
Hospitalized patients with severe COVID-19 have an increased incidence of insulin resistance, impaired beta cell function, glucose intolerance (prediabetes), and overt type 2 diabetes (T2D) compared to non-hospitalized patients with COVID-19 and COVID-19 negative individuals on long-term follow up. Type: Observational Start Date: Jul 2023 |
Strategies and Treatments for Respiratory Infections &Amp; Viral Emergencies (STRIVE): Immune Modulation...
University of Minnesota
COVID-19
COVID-19 can trigger a dysregulated immune response, and previous studies have shown that
immune modulation can improve outcomes in hospitalized patients. This trial is designed
to determine whether intensification of immune modulation early in the course of the
disease (while patients are on low... expand
COVID-19 can trigger a dysregulated immune response, and previous studies have shown that immune modulation can improve outcomes in hospitalized patients. This trial is designed to determine whether intensification of immune modulation early in the course of the disease (while patients are on low flow oxygen) with abatacept (active arm) combined with standard of care (SOC) improves recovery as compared with placebo + SOC (placebo arm). For both groups, intensification of immunomodulation will be provided as part of SOC in case of signs of disease progression (patient requires high flow nasal oxygen (HFNO) or more support) and/or if the patient has rapidly increasing oxygen requirement. Type: Interventional Start Date: Jul 2023 |
The Impact of Chiropractic on Long COVID-19
Life University
Long COVID
The purpose of this waitlist-controlled, single-blind, one-way crossover, pilot trial is
to evaluate the potential effects of ~8 weeks of chiropractic care on patient-reported
fatigue and the autonomic nervous system in adults with long COVID. This study will allow
us to estimate the standard deviation... expand
The purpose of this waitlist-controlled, single-blind, one-way crossover, pilot trial is to evaluate the potential effects of ~8 weeks of chiropractic care on patient-reported fatigue and the autonomic nervous system in adults with long COVID. This study will allow us to estimate the standard deviation of the primary endpoint in our population with which a formal power calculation for a future randomized, controlled trial can be performed. Type: Interventional Start Date: Jan 2025 |
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